5-Amino-1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme involved in the methylation of nicotinamide. NNMT has been identified in published research as being significantly overexpressed in adipose tissue, and studies have explored its role in cellular NAD+ salvage pathway regulation. Preclinical research published in Biochemical Pharmacology has examined 5-Amino-1MQ's effects on NNMT enzymatic activity in adipocyte differentiation models and its influence on SAM (S-adenosyl methionine) and NAD+ metabolite ratios in cell-based assays. Supplied as a >99% purity solid compound.

This product is intended strictly for laboratory research use only. It is not approved for human or veterinary consumption or for use in diagnostic or therapeutic procedures.

• Purity: >99%
• Form: Lyophilised powder
• Intended use: Laboratory research only